Associations of 100% fruit juice versus whole fruit with hypertension and diabetes risk in postmenopausal women: Results from the Women’s Health Initiative
Brandon Auerbach, MD, MPH; Alyson J. Littman, PhD, MPH; Lesley Tinker, PhD, RD; Joseph Larson, MS; et. al.
Preventive Medicine. 2017 Sep 6. pii: S0091-7435(17)30315-8. doi: 10.1016/j.ypmed.2017.08.031. [Epub ahead of print]
This is an unedited manuscript accepted for publication
Key Findings: Longitudinal analysis of food frequency questionnaires of postmenopausal women enrolled in the Women’s Health Initiative between 1993-1998. Standardized questionnaires assessed outcome every 6-12 months during an 7.8 year follow up. Study evaluated incidence of hypertension (n=36,314 incident cases/80,539 total participants) and diabetes (n=11,488 incident cases/114,219 total participants). In multivariable analyses there was no significant association comparing the highest to lowest quintiles of 100% fruit juice consumption (8oz/day compared to none) and incident hypertension or diabetes. There was also no significant association between whole fruit consumption and incident hypertension or diabetes. Consuming moderate amounts of 100% fruit juice (8oz./day) or whole fruit was not significantly associated with risk of hypertension or diabetes among postmenopausal US women.